首页工具

登录

搜索结果

Search Results for " tissue plasminogen activator "

Targets Recommended: Others Serine Protease Influenza Virus Proteasome

15

抑制剂 & 化合物

10

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T3359	Aprotinin 抑酶肽,抑肽酶,Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin	Others; Serine Protease; Influenza Virus; Proteasome	Microbiology/Virology; Others; Proteases/Proteasome; Ubiquitination
	Aprotinin (Traskolan) 是分离自牛肺的一种广谱丝氨酸蛋白酶抑制剂，可抑制多种不同酯酶和蛋白酶的活性。
T69890	PS-519
	PS-519 is a human tissue plasminogen activator and proteasome inhibitor.
T70734	U46,195
	U46,195 stimulates the production of tissue-type plasminogen activator, and is a PAF antagonist.
T68659	Valyl-glycyl-arginine-4-nitroanilide
	Valyl-glycyl-arginine-4-nitroanilide is a tissue plasminogen activator.
T69319	U 34599
	U 34599 stimulates the production of tissue-type plasminogen activator.
T71851	5-trans-Prostaglandin E2
	5-trans-Prostaglandin E2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator. It also inhibits platelet aggregation in human PRP.
T41085	UK122 UK122
	UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA), plasmin, thrombin, and trypsin (all IC50 >100 μM). Functioning as a 4-oxazolidinone analogue, UK122 is an anticancer agent that effectively inhibits cancer cell migration and invasion.
T70810	THR-18
	THR-18 is an 18-mer peptide derived from the sequence of human plasminogen activator inhibitor 1 (PAI-1), having the ability to bind to a site of tissue plasminogen activator (tPA) distal to its catalytic site and uncouple the beneficial clot-dissolving properties of tPA from its deleterious non-fibrinolytic effects.
T40614	LCKLSL
	LCKLSL, an N-terminal hexapeptide, acts as a competitive inhibitor of annexin A2 (AnxA2), effectively preventing the binding of tissue plasminogen activator (tPA) to AnxA2 while also inhibiting the generation of plasmin. In addition, LCKLSL exhibits anti-angiogenic properties.
T11152	Edaravone-d5 MCI-186 D5	Others	Others
	Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the original compound's attributes while offering isotopic labeling benefits.
T68513	BSc2118
	BSc2118 is a potent proteasome inhibitor. BSc2118 shows significant antimyeloma activity and may be considered as a promising agent in cancer drug development. BSc2118 is also a promising new candidate for stroke therapy, which may in addition alleviate recombinant tissue-plasminogen activator-induced brain toxicity.
T64287	Reteplase
	Reteplase (BM 06.022) 是一种重组纤溶酶原 (plasminogen) 激活剂，由人组织型纤溶酶原激活剂的 kringle 2 和蛋白酶结构域构成。Reteplase 能够将纤溶酶原转化为纤溶酶，促使血栓溶解。Reteplase 通过 DNA 技术在大肠杆菌中产生的 t-PA 突变体，未糖基化。
T78018	Plasminogen
	Plasminogen是一种可由尿激酶血浆蛋白原激活剂(uPA)或组织血浆蛋白原激活剂(tPA)裂解激活的分泌性蛋白，生成血浆蛋白，该酶可以广泛裂解纤维蛋白及其他ECM成分。作为促炎调节剂，Plasminogen能促进急性及糖尿病相关伤口愈合。该蛋白在伤口愈合、炎症和低纤溶酶原血症的研究中有重要应用。
TP2482	LCKLSL acetate LCKLSL acetate(533902-29-3 free base)	Annexin A	GPCR/G Protein
	LCKLSL acetate 是一种竞争性膜联蛋白 A2 (AnxA2) 抑制剂。 LCKLSL acetate 有效抑制组织纤溶酶原激活剂 (tPA) 与 AnxA2 的结合和纤溶酶的产生。 LCKLSL acetate 具有抗血管生成作用。
T78015	LCKLSL hydrochloride
	LCKLSL hydrochloride为N端六肽，作为膜联蛋白A2（AnxA2）的竞争性抑制剂，有效阻止组织纤溶酶原激活物（tPA）与AnxA2结合。此化合物还能够抑制纤溶酶生成，并表现出抗血管生成活性。

化合物

Cat.No: T3359

Synonym: 抑酶肽,抑肽酶,Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin

Target: Others, Serine Protease, Influenza Virus, Proteasome

Cat.No: T69890

Cat.No: T70734

Valyl-glycyl-arginine-4-nitroanilide

Cat.No: T68659

Cat.No: T69319

5-trans-Prostaglandin E2

Cat.No: T71851

Cat.No: T41085

Synonym: UK122

Cat.No: T70810

Cat.No: T40614

Cat.No: T11152

Synonym: MCI-186 D5

Target: Others

Cat.No: T68513

Cat.No: T64287

Cat.No: T78018

Cat.No: TP2482

Synonym: LCKLSL acetate(533902-29-3 free base)

Target: Annexin A

LCKLSL hydrochloride

Cat.No: T78015

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00938	tPA Protein, Human, Recombinant TPA,plasminogen activator, tissue...	Human	HEK293 Cells
	tPA Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 28 kDa and the accession number is P00750-1.
TMPJ-00332	tPA Protein, Human, Recombinant (His) TPA,T-PA,t-plasminogen activator,Tissu...	Human	HEK293 Cells
	Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, PLAT plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and in modulating the post-tra...
TMPY-00937	tPA Protein, Human, Recombinant (hFc) TPA,T-PA,plasminogen activator, tissue...	Human	HEK293 Cells
	tPA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.5 kDa and the accession number is P00750-1.
TMPY-02898	tPA Protein, Mouse, Recombinant (hFc) plasminogen activator, tissue,AU0...	Mouse	HEK293 Cells
	tPA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.4 kDa and the accession number is P11214.
TMPK-00810	tPA Protein, Mouse, Recombinant (His) PLAT,Reteplase,t-PA,tPA,Alteplase	Mouse	HEK293 Cells
	Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism.
TMPJ-00625	Serpin E1 Protein, Mouse, Recombinant (His) Pai1,Planh1,Plasminogen activator inhibito...	Mouse	HEK293 Cells
	Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
TMPJ-00501	CLEC3B Protein, Human, Recombinant (His) Plasminogen Kringle 4-Binding Protein,Tetranectin,T...	Human	HEK293 Cells
	C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. In addition, CLEC3B may be involved in the packaging of molecules destined for exocytosis. Also, CLEC3B is best known as a...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple...
TMPH-02834	PAI-1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of ...
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His) Plasminogen Activator Inhibitor 3,Acrosoma...	Human	HEK293 Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes o...

重组蛋白

tPA Protein, Human, Recombinant

Cat.No: TMPY-00938

Species: Human

Expression System: HEK293 Cells

tPA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00332

Species: Human

Expression System: HEK293 Cells

tPA Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00937

Species: Human

Expression System: HEK293 Cells

tPA Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02898

Species: Mouse

Expression System: HEK293 Cells

tPA Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00810

Species: Mouse

Expression System: HEK293 Cells

Serpin E1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00625

Species: Mouse

Expression System: HEK293 Cells

CLEC3B Protein, Human, Recombinant (His)

Cat.No: TMPJ-00501

Species: Human

Expression System: HEK293 Cells

Serpin A5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02832

Species: Mouse

Expression System: Baculovirus Insect Cells

PAI-1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02834

Species: Mouse

Expression System: E. coli

Serpin A5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00490

Species: Human

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼